Overview

LUOFUCON® Collagen Wound Dressing is an advanced sterile, single-use wound management solution composed of 100% bovine Type I collagen with no fillers. Designed with excellent tissue affinity and biocompatibility, the dressing leverages the natural healing power of collagen to promote wound repair, protect the wound bed, and support a moist healing environment.

Composition and Structure

The dressing consists of a porous matrix of cross-linked bovine collagen, maintaining the original triple-helix structure. This structure ensures high biocompatibility, strong mechanical strength, and superior absorption capacity—capable of absorbing up to 38 times its own weight in wound exudate. Once hydrated with exudate or sterile water, the dressing transforms into a soft, conformable gel sheet that covers and protects the wound, while forming a physical barrier against the external environment.

The Role of Collagen in Wound Healing

Collagen is the most abundant protein in animal tissues, accounting for up to 90% of dermal dry weight. It is a crucial component of the extracellular matrix (ECM), providing structural support and regulating cellular activities. In wound healing, collagen plays vital roles across all phases:

• Chemotaxis: Attracts fibroblasts and keratinocytes to the wound site.
• Angiogenesis & Reepithelialization: Encourages new blood vessel growth and skin repair.
• Matrix Balance: Helps regulate matrix metalloproteinases (MMPs), which, when uncontrolled, can degrade healthy tissue and delay healing.

Chronic wounds often result from excess MMP activity, stalling healing at the inflammatory stage. Collagen dressings such as LUOFUCON® help balance protease activity, protect viable tissue, and provide a scaffold for cellular proliferation and migration.

Benefits of Collagen Dressings

Collagen wound dressings provide multiple clinical benefits:

• Inhibit or deactivate excess MMP activity.
• Stimulate fibroblast production and migration.
• Improve uptake and bioavailability of fibronectin.
• Preserve key wound-healing cells including macrophages and epithelial cells.
• Maintain a stable chemical and thermal wound environment.
• Provide a porous scaffold that facilitates tissue regeneration.

Advantages of LUOFUCON® Collagen Wound Dressing

• 100% Type I bovine collagen, no chemical additives or fillers.
• Excellent absorption and gel formation for moist wound healing.
• High mechanical strength, flexibility, and ease of application.
• Fully absorbable, non-pyrogenic, and biocompatible.
• Enhanced enzyme resistance and structural integrity through safe cross-linking technology.
• Can be layered or trimmed precisely to wound size.
• Suitable for use as a hemostatic dressing on bleeding surface wounds.

Indications

LUOFUCON® Collagen Wound Dressing is indicated for the management of:

• Full- and partial-thickness wounds
• Pressure ulcers
• Venous ulcers and mixed vascular ulcers
• Diabetic ulcers
• Partial-thickness burns
• Donor sites
• Abrasions and traumatic wounds
• Dehisced surgical incisions
• Wounds healing by secondary intention

Contraindications

• Patients with known sensitivity to bovine collagen
• Third-degree burns
• Actively infected wounds

Precautions

• Do not use on uncontrolled infections.
• Do not use if package is damaged or past expiration date.
• Do not reuse, re-sterilize, or retain unused portions once opened.
• Discontinue use and consult a physician if adverse reactions occur.

Conclusion

LUOFUCON® Collagen Wound Dressing combines scientific innovation with the body’s natural healing mechanisms to support effective wound care. By harnessing the regenerative power of collagen, this dressing helps manage complex wounds, restore tissue balance, and promote faster, healthier healing outcomes.